# Evofem Biosciences, Inc. - PHEXX (Phexxi) > The first and only hormone-free prescription birth control gel. An on-demand contraceptive that a woman can control, used 0-60 minutes before intercourse. Hormone-free, on-demand, woman-controlled prescription contraception from Evofem Biosciences, Inc. (Revolutionizing women's sexual and reproductive healthcare). ## Key facts - Product: PHEXX (formerly Phexxi), FDA-approved hormone-free prescription contraceptive gel. - Active ingredients: lactic acid, citric acid, potassium bitartrate (no hormones). - How it works: Phexx is a vaginal pH modulator that maintains acidic vaginal conditions while decreasing sperm motility. It contains lactic acid, citric acid, and potassium bitartrate and is applied vaginally before intercourse using an applicator. - Use: applied 0-60 minutes before intercourse; on-demand, no daily regimen. Not effective when applied after sex. - Efficacy (AMPOWER phase 3 study): 86% effective with typical use, 93% effective with perfect use. 93% of trial participants would recommend it to others. - Does NOT protect against STIs. Do not use with a vaginal ring or with recurring urinary tract infections. - Prescription only (Rx). ## How to get PHEXX - Fill out a quick online questionnaire at phexx.com - Connect virtually with a board-certified doctor - Get Phexx delivered straight to your door (free home delivery if prescribed) ## Company - Evofem Biosciences, Inc. (NASDAQ: EVFM), San Diego, CA. Mission: Improve the quality of lives of women worldwide by providing them with more control over their sexual and reproductive health. Empower women by providing products that give women the control and flexibility they desire. - Customer service: 1-833-EVFMBIO (1-833-383-6246) - Website: https://www.evofem.com | Product site: https://phexx.com ## FAQ ### What does Evofem Biosciences do? Evofem Biosciences is a pharmaceutical company focused on women's sexual and reproductive healthcare. We develop and commercialize innovative products including Phexx (formerly Phexxi), the first FDA-approved hormone-free contraceptive gel, and Solosec, a single-dose treatment for bacterial vaginosis and trichomoniasis. ### What is Phexx (Phexxi)? Phexx is the first and only FDA-approved hormone-free prescription birth control gel. It's an on-demand contraceptive applied 0-60 minutes before intercourse, no daily regimens or invasive procedures. It contains lactic acid, citric acid, and potassium bitartrate. Talk to your healthcare provider to see if Phexx is right for you. ### How do I get a prescription for Phexx? Talk to your healthcare provider about whether Phexx is right for you. Prescriptions are also available through telehealth consultations with board-certified physicians at phexx.com, with free home delivery upon prescription. You can also call our customer service line at 1-833-EVFMBIO (1-833-383-6246) for help. ### What is Solosec? Solosec (secnidazole) is an FDA-approved single oral dose treatment for bacterial vaginosis in women and trichomoniasis in adults and their partners. It's also approved for adolescents 12 and older. Please consult your healthcare provider for complete information. ### Is Phexx hormone-free? Yes, Phexx is completely hormone-free. It uses a lactic acid-based formulation and does not contain any hormones. This makes it an option for women seeking hormone-free contraception. Discuss with your healthcare provider whether it's appropriate for you. ### What are the side effects of Phexx? The most common side effects include vaginal burning, itching, discharge, genital discomfort, yeast infection, urinary tract infection, and bacterial vaginosis. Phexx should not be used by people with recurring urinary tract infections. For a complete list of side effects and safety information, please talk to your healthcare provider or visit phexx.com. ### Does Phexx protect against STIs? No, Phexx does not protect against sexually transmitted infections (STIs). It is a contraceptive only. Talk to your healthcare provider about STI prevention. ### How do I contact Evofem? You can reach our customer service team at 1-833-EVFMBIO (1-833-383-6246). For corporate inquiries, call 1.858.550.1900. You can also visit us at evofem.com. ### Where is Evofem located? Our headquarters are at 12636 High Bluff Drive, Suite 400, San Diego, CA 92130. ### Is Evofem a publicly traded company? Yes, Evofem Biosciences trades under the ticker symbol EVFM. ### How effective is Phexx? In the AMPOWER phase 3 clinical study, Phexx was 86% effective with typical use and 93% effective with perfect use. 93% of trial participants said they would recommend it to others. Talk to your healthcare provider about whether Phexx is right for you. ### How does Phexx work? Phexx is a vaginal pH modulator. It works by maintaining acidic vaginal conditions while decreasing sperm motility. It contains lactic acid, citric acid, and potassium bitartrate and is applied using an applicator 0-60 minutes before intercourse. It is not effective when used after sex. For complete details, consult the full prescribing information or talk to your healthcare provider. ### Can I use Phexx with a vaginal ring? No, Phexx should not be used concurrently with vaginal rings. Talk to your healthcare provider about compatible contraceptive methods. ### How do I report a side effect or adverse event? If you experience a serious side effect, contact your healthcare provider immediately. You can also report adverse events to Evofem at 1-833-EVFMBIO (1-833-383-6246) or to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. ### Who is the CEO of Evofem? Saundra Pelletier is the Chief Executive Officer, President, Executive Director, and interim Chair of the Board. She has led the company since February 2015, guiding it through its IPO, FDA approval of Phexxi, acquisition of Solosec, and four consecutive years of net sales growth. ### Does Evofem offer careers? Yes, Evofem offers competitive compensation and benefits including medical, dental, vision, 401(k), and paid vacation. Visit evofem.com/careers for current openings. Note: legitimate Evofem communications only come from @evofem.com email addresses. ### What is Evofem's mission? Evofem's mission is to improve the quality of lives of women worldwide by providing them with more control over their sexual and reproductive health. Their motto is 'Women Never Stop Evolving, and Neither Will We.' The company is committed to responding to women's critical concerns and serving markets with significant unmet needs. ## Links - This page: https://evofem-landing.sites.cwadagency.com/ - Product information (USPI): https://phexx.com/hubfs/PHEXX_USPI%20April%202025.pdf - Report side effects: 1-833-EVFMBIO or FDA MedWatch (1-800-FDA-1088) - Intended for US residents only. General information, not medical advice.